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IVF Meds used during a Gestational Surrogate Cycle

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IVF Meds used during a Gestational Surrogate Cycle

So, how many meds could I take and why?


Gestational Surrogate and IVF Meds


A Summary of The IVF Medication used during an IVF cycle





One of the big factors in deciding to become a gestational surrogate is the amount of meds used during the IVF Cycle. Clinics use a mix of injectables, patches, pills, suppositories and nasal sprays. I am going to attempt to cover what the meds are and then give several examples of the total medicine consumption used during one IVF cycle. The examples will show you the variations of what you could expect to go through. Lets start with the meds and their purpose.


Gonadotropin releasing hormone (GnRH) agonists (Synarel, Lupron) are medications that inhibit the brain from secreting hormones that control the menstrual cycle. The ovaries enter into a state of rest, and the patient's cycle can be completely controlled. These medications prevent premature ovulation and allow the patient's cycle to be coordinated as needed.


Lupron is a subcutaneous injection and Synarel is a nasal spray. They are usually started one week before the gestational surrogates period is expected or in the very beginning of the cycle. These medications are usually well-tolerated, and most women do not have any side effects when taking these medications for a short time. However, some women may have hot flashes, fatigue, headaches, irritability or nausea.


Estrogen is the hormone that thickens the lining to the endometrium (inner wall of the uterus). Estrodial can be given as an oral tablet, intramuscular injection, or patch on the skin. Some women may experience vaginal irritation, dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased or decreased interest in sex, or breast tenderness.


Progesterone is the hormone produced by the ovary after ovulation. This medication can be given to improve the uterine lining, which may improve implantation of the embryo. It is usually started in the second half of the cycle, several days before the embryo transfer. Progesterone can be given as an intravaginal suppository, oral capsule, or an intramuscular injection. Side effects can include bloating, irritability, and breast tenderness.


Antibiotics (doxycycline) and/or Steroids (methylprednisone) may be used as anti-rejection tactics.


So, exactly how many of these meds can a gestational surrogate expect to take?


As I have stated before, this question has several answers according to the clinic and the gestational surrogate herself. Everyone's body reacts differently to the meds and so the total amount will vary from person to person.


Total meds used by Dawn (@Sunrise) during her fifth IVF cycle.


35 BCP's

Lupron Shots 8@10Units & 15@5Units

12 Doxycycline Pills

6 Medrol Pills

1 Valium

15 PIO IM Shots

141 Estrogen Patches

82 Progesterone Suppositories

I did not count the daily baby aspirin nor the daily prenatal vitamin.



Here are the meds used during Trena's (TrenaT) recent cycle. She is a gestational surrogate for M & K.


6 weeks BCP

12 Lupron shots at 15 units

12 Lupron shots 10 units

Baby Aspirin Daily

Cipro- 5 days 10 pills

E2V- 3 weeks before transfer x2 a week .4cc til 10 weeks gest.

PIO 1cc daily 5 days pre transfer til 12 weeks

Progestrone/Estrogen supps daily from transfer til 12 weeks

400 mg Prometrium daily from 5 days pretransfer till 12 weeks

Medrol 8 mg for 12 days, 16 mg til about 6 weeks gest.

Folgard Daily

Erthromycin daily 10 days


Additonal Questions?


If you have any other questions that you need answered, you can register to become a member. Then post the question on the message boards where you can get answers from several experienced gestational surrogates Another option is that you can just post a question on the "Ask a Gestational Surrogate" section. Registration is not required to post a question in this section and it will be answered by one surrogate.


Information gathered from Several Community Members

If you have a list of meds from your cycle,

please mail them to

AAS username: @Sunrise

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